A revolutionary DNA-based treatment now offers hope to millions seeking safer ways to lower cholesterol. Researchers have designed a therapy that targets the PCSK9 gene, which plays a key role in cholesterol regulation. This innovative approach uses polypurine hairpins to naturally boost cholesterol uptake by cells, dramatically slashing harmful lipid levels in the bloodstream.
How the New Therapy Works
Unlike traditional statins, which can have unpleasant side effects, this DNA-based method focuses on silencing the PCSK9 gene. By doing so, the therapy reduces the production of PCSK9 proteins that normally limit the body’s ability to clear cholesterol. As a result, cells become more efficient at removing cholesterol from the blood. Tests in animal models have shown a nearly 50% reduction in both PCSK9 and cholesterol levels—without the common side effects associated with statins.
A Safer, More Effective Alternative
This advancement could change the way we manage heart health. People who are intolerant to statins or worry about side effects may soon have a new, natural option. As research progresses, this DNA-based therapy could become a game-changer in the fight against cardiovascular disease.
Sources:
ScienceDaily: New treatment cuts cholesterol by nearly 50%, without statins or side effects
