Ancient DNA continues to shape our lives today, and a recent discovery shines new light on how extinct human relatives contributed to our survival.
The Denisovan DNA Legacy
Researchers have identified a gene called MUC19, which early humans inherited from Denisovans through ancient interbreeding. This gene appears at remarkably high frequencies in both ancient and modern Indigenous populations across the Americas.
Genetic Advantages in a New World
Scientists believe MUC19 played a key role in helping Indigenous ancestors adapt as they migrated into unfamiliar territories. The gene likely provided crucial immune defense, helping early humans combat new pathogens they encountered in the Americas. This adaptation may have given them a survival advantage, allowing their communities to flourish.
Remarkably, this research also shows how interbreeding with both Denisovans and Neanderthals enriched our genetic toolbox. These ancient DNA gifts continue to influence our biology, shaping the diversity and resilience found in people today.
Sources:
ScienceDaily: Extinct human relatives left a genetic gift that helped people thrive in the Americas
