Groundbreaking Discovery: Lung Tumors and Immune System Manipulation
Lung tumors don’t just hide from your immune system—they actively reshape it at its very source. The latest research from the Icahn School of Medicine at Mount Sinai, published in Nature, reveals that lung tumors can rewire immune cells in the bone marrow even before these cells reach the tumor site. This discovery could revolutionize how we approach cancer immunotherapy and prevention.
What This Means for Cancer Treatment
Researchers found that lung tumors send signals to the bone marrow, altering the development and function of immune cells. These pre-conditioned cells then travel to the tumor and may help the cancer evade immune attacks. This manipulation starts long before the immune cells even encounter the cancerous tissue.
This insight opens up a promising new target: if scientists can block or reverse these tumor-driven changes in the bone marrow, they may boost the effectiveness and durability of current immunotherapies. Targeting the root of immune cell formation could provide lasting protection against cancer progression.
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