Physical Stress Triggers Transformation in Cancer Cells
Recent research uncovers how physical pressure from surrounding tissues activates invasive behavior in cancer cells. Scientists found that when cancer cells experience mechanical stress, they undergo significant changes at the epigenetic level. This stress rewires their genetic regulation, making them more adaptable and aggressive as they spread throughout the body.
Understanding the Mechanism Behind Cancer Cell Adaptability
Cancer cells can shift their characteristics rapidly, which complicates treatment and allows them to metastasize more easily. The study reveals that mechanical forces in the tumor microenvironment play a crucial role in these shifts. By influencing epigenetic programming, mechanical stress makes cancer cells more invasive and resistant to therapy. This discovery opens new avenues for targeting how cancer adapts and spreads, potentially leading to more effective treatments in the future.
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How Physical Stress Pushes Cancer Cells Into Dangerous New States
