Scientists at the European Molecular Biology Laboratory (EMBL) have introduced a pioneering technology called SDR-seq. This advanced tool allows researchers to analyze genetic variants at the single-cell level and directly link them to disease-related insights, marking a major milestone in genomics research.
What is SDR-seq?
SDR-seq stands for Simultaneous DNA and RNA sequencing at the single-cell level. This tool enables scientists to capture both the genetic code (DNA) and its activity (RNA) from the same cell. As a result, researchers can observe how specific genetic variants influence gene expression and cellular functions. This level of detail greatly enhances our ability to understand complex diseases such as cancer, neurological disorders, and autoimmune conditions.
Impact on Disease Research
By linking genetic changes to their effects in individual cells, SDR-seq opens new doors for precision medicine. It provides a clearer picture of how mutations drive disease, which could lead to more targeted therapies and better diagnostic tools. The EMBL team’s innovation paves the way for breakthroughs in how we study and treat genetic diseases.
